There have be quite a few genes associated beside rarer forms of type 2 diabetes-The majority are transcription factors, such as hepatocyte nuclear factor 4alpha (HNF-4alpha), HNF-1alpha, insulin promoter factor-1 (IPF-1), HNF-1beta, and NEUROD1. But, these are found, as said in the past, in more severe and special forms of inherited type 2 diabetes.
For the more adjectives form of late-onset diabetes, it is more subtle, and therefore not as natural to find clear genetic traits. However, a few genes have be found to have modifications surrounded by some people, resembling calpain 10, PPARgamma, KCJN11, and insulin itself, and some evidence shows that genes involved in the insulin receptor pathway may influence type 2 diabetes, close to adiponectin, IRS-1, and some others may also influence the susceptibility to T2DM.
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